Connect with us

Medical Science

COVID19: Single dose of vaccine sufficient for those already infected; Study

(Asian News Hub) – A study by Hyderabad’s AIG Hospitals has claimed that a single dose of COVID-19 vaccine is sufficient for those already infected by the disease before.

The hospital said it conducted a study on 260 healthcare workers who got vaccinated between January 16 and February 5 to assess the immunological memory response in all those patients. All patients were given the Oxford-Serum vaccine Covishield.

Two significant observations came out of the study, which has been published in the International Journal of Infectious Diseases, a peer-reviewed journal.

The previously infected group (people who got infected with COVID-19) showed a greater antibody response to a single dose of vaccine compared with those who had no prior infection.

It also revealed that Memory T-cell responses elicited by a single dose of vaccine were significantly higher in the previously infected group compared with those who had no prior infection.

It was concluded that higher memory T and B-cell responses in addition to higher antibody response with a single dose of vaccine given at 3-6 months after recovery from COVID-19 may be considered at par with two doses of vaccine for individuals already infected with COVID-19.

“The results show that people who got infected with COVID-19 need not take two doses of vaccine yet with a single dose can develop robust antibody and memory cell response at par with two-doses for those who didn’t get the infection.

This will significantly help at a time when there’s a shortage of vaccine in the country and more people can be covered using the saved doses,” said Dr. D Nageshwar Reddy, Chairman, AIG Hospitals, and one of the co-authors in the study.

“Once we attain the requisite number of people vaccinated for achieving herd immunity, these patients who got infected and received only one dose can take the second dose of the vaccine.

At this point, all our strategies should be directed at the widespread distribution of available vaccines and to include the maximum number of people at least with a single dose,” he added.

During the second Covid wave when cases were growing exponentially; the vaccination rate took a downturn. As of April 27, when the growth rate of active infection was 5%, the growth of vaccinated people was just 1.4 per cent.

“We need to modify vaccination strategy based on scientific evidence and with the objective that a larger set of the population can be covered in the shortest duration,” he said.

WITH IANS INPUTS

Medical Science

Serosurvey would determine impact of possible 3rd Covid wave on children: DAK

(Asian News Hub) – Doctors Association Kashmir (DAK) on Saturday said serosurvey of pediatric population in the valley would determine the impact of possible third Covid-19 wave on children.

Serosurvey of children will give us a fair estimate of their vulnerability in predicted third wave,” said DAK President and influenza expert Dr Nisar ul Hassan.

“Serosurvey involves testing blood samples of individuals for antibodies that are developed after an infection,” he said.

“This will give us an idea about the percentage of pediatric population who might have developed natural immunity.”

Dr Hassan said recently, a serosurvey of general population including children aged 7 to 17 years has been completed in Kashmir, the results of which are awaited.  The sample size per district in the age group 7 to 11 was 40 and it was 80 in 12-17 age group.

“The survey needs to be extended to the age group of 0 to 6 years and the sample size per district should be 500 to 1000 to get a clearer picture of the actual percentage of children who have developed immunity against Covid-19,” he said.

Dr Hassan said there are speculations that children would be affected more than adults in possible third wave as this is the population group in which there is no vaccine yet.

“However, various serosurveys have dismissed the claim that the next wave will be affecting children exclusively,” he said.

“A pediatric serological study conducted by AIIMS, New Delhi at five different sites found that 55.7 percent children had developed antibodies,” DAK President said.

“The study found that seroprevalence of children and adults in the same regions were almost similar.”

“Another study conducted by PGI Chandigarh revealed that 69 percent of children had antibodies against Covid-19,” he said.

“These children had remained either asymptomatic or mildly symptomatic during the infection.”

“The data of the two surveys prove that children have acquired natural immunity against the virus and it is highly unlikely that the third wave will affect children more than adults,” said Dr Nisar.

“This is a big relief. Because the apprehensions expressed by several health experts about the third wave primarily targeting children had left people worried,” he said.

“But, we can’t derive conclusions on the data from other regions. We need to have our own data based on which decisions can be made ahead of the feared third wave,” he added.

Continue Reading

Medical Science

Israel reports Pfizer COVID-19 vaccine effectiveness against infection down to 40%

(Asian News Hub) – The Health Ministry said Thursday that the effectiveness of the Pfizer COVID-19 vaccine in preventing infection and mild symptoms has dropped to 40%, according to new data collected over the past month as the delta variant spreads in Israel.

In a televised address, Prime Minister Naftali Bennett meanwhile called on Israelis who haven’t been vaccinated to do so as soon as possible.

“The Israeli government is investing billions so that there is a vaccine available in every location in the country, and there are still a million Israelis who simply refuse to be vaccinated,” he said. “The vaccine refusers are endangering their health, their surroundings and all Israeli citizens. If a million Israelis continue to be unvaccinated, this will force the others to shut themselves in at home.”

The effectiveness of the vaccine in preventing hospitalizations and severe symptoms stands at 88% and 91%, respectively, the ministry said.

With inputs from Haaretz

Continue Reading

Medical Science

Scientists discover more than 30 viruses frozen in ice, most never seen before

(Asian News Hub) – A group of scientists discovered ancient viruses frozen in two ice samples taken from the Tibetan Plateau in China, and most of them are unlike anything ever seen before.

The findings, published Wednesday in the journal Microbiome, came from ice cores taken in 2015 that scientists said began to freeze at least 14,400 years ago.

“These glaciers were formed gradually, and along with dust and gases, many, many viruses were also deposited in that ice,” Zhi-Ping Zhong, lead author and researcher at the Ohio State University Byrd Polar and Climate Research Center, said in a statement. “The glaciers in western China are not well-studied, and our goal is to use this information to reflect past environments. And viruses are a part of those environments.”

When researchers analyzed the ice, they found genetic codes for 33 viruses. Of the 33, genetic codes for four of them showed they are part of virus families that typically infect bacteria. Up to 28 were novel, meaning they had never before been identified.

The group said it doesn’t believe the viruses originated from animals or humans but came from the soil or plants. The scientists said roughly half of them survived because of the ice.

“These are viruses that would have thrived in extreme environments,” said Matthew Sullivan, co-author of the study and director of Ohio State’s Center of Microbiome Science.

“These viruses have signatures of genes that help them infect cells in cold environments – just surreal genetic signatures for how a virus is able to survive in extreme conditions.”

Sullivan said the technology used to study microbes and viruses inside the ice would lead to looking for similar genetic sequences in other extreme ice environments, possibly on Mars.

Senior author of the study Lonnie Thompson said the discovery of the viruses in glaciers of ice will help researchers understand how they respond to climate change.

“We know very little about viruses and microbes in these extreme environments and what is actually there,” Thompson said. 

“The documentation and understanding of that is extremely important.”

AGENCY

Continue Reading

Trending